Postdoctoral Position (m/f/d) in Cardio-Immunology - #999391

We offer

The Comprehensive Heart Failure Center (CHFC) and the DFG-funded Collaborative Research Centre (CRC) 1525 "Cardio-immune Interfaces" at the University Hospital Würzburg form a unique, nationwide hub dedicated to advancing the emerging field of cardio-immunology. Within this interdisciplinary network, we are seeking a highly motivated Postdoctoral researcher (m/f/d, E13, 100%) to work on a project characterizing the adaptive immune landscape in cardiovascular disease. As part of this network, you will benefit from close collaborations with clinical departments in the hospital, and from a supportive, structured mentoring environment designed to foster career development.

Your Tasks

• Decode the cardio-immune crosstalk by tracking antigen-specific T cells longitudinally in heart failure patients and mechanistically modeling their roles in experimental mouse models.
• Bridge experimental and computational biology to investigate how pathogenic T cells functionally evolve and where they localize during disease progression.
• Study antigen-specific T cell responses using spectral flow cytometry, single-cell RNA/TCR sequencing, functional TCR screening, and high-resolution in situ spatial transcriptomics (Xenium platform).
• Map precise antigen-specific responses within cardiac niches to provide a foundation for patient stratification and the development of targeted, immune-based diagnostic tools in heart failure.
  
  

Your Profile

• PhD degree in Immunology, Cell Biology, or a related life sciences discipline.
• Extensive hands-on experience with mouse models (animal handling experience or FELASA B is a plus) and human clinical samples.
• Strong motivation to independently analyze single-cell and spatial sequencing data.
• Excellent organizational skills, team spirit, and English fluency.
  
  

This Is What You Can Look Forward To

• Challenging, diverse and evolving area of responsibility
• Attractive salary according to TV-L incl. annual special payment
• Training and Continuing Education
• Retirement Pension Plan
• Company daycare center with extended opening hours
• Company sports program
• Flexible Working Hours
• JobBike
• Corporate Benefits
  
  

Become part of the team: Apply now!

Dr. Diyaa Ashour

Principal Investigator

Tel: +49931 201 46516

In the case of a university degree from a non-EU country, a long version of the certificate evaluation from the Central Office for Foreign Education is required.

Remuneration is in accordance with the relevant collective agreements. Severely disabled applicants will be given preference if they are otherwise equally qualified.

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